What is one significant difference between a corporate bond and a corporate loan?

The significant difference highlighted in the correct choice revolves around the nature of the security backing corporate loans compared to corporate bonds. Corporates often secure loans with a pledge of collateral, which can include all of the company's assets, to provide lenders with a safety net in case of default. This type of security is a common practice in loan agreements to mitigate risk for the lender.

On the other hand, corporate bonds may not always be secured by assets. Bonds can be either secured, meaning they are backed by specific collateral, or unsecured, standing solely on the issuer's creditworthiness. This distinction is crucial; it indicates that while some bonds might have a backing, it is not a universal characteristic as it is with many loans.

This understanding of collateral requirements helps clarify the risk profiles and investment mechanics associated with corporate debt instruments. It's essential for investors and financial professionals to recognize these differences when assessing risk and making investment decisions.